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arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)

State Icon Reaction EC-Number Confidence maximal confidence score from EnzymeDetector
[glycerolipid]-di-homo-gamma-linolenate + ferricytochrome_b5 + O2 + H+ <=> [glycerolipid]-arachidonate + ferricytochrome_b5 + H2O 1.14.19.30 acyl-lipid (8-3)-desaturase

(11Z,14Z)-icosa-11,14-dienoyl-CoA + NADP+ <=> (2E,11Z,14Z)-icosatrienoyl-CoA + NADPH + H+ 1.3.1.93 very-long-chain enoyl-CoA reductase

(3R,11Z,14Z)-3-hydroxyicosadienoyl-CoA <=> (2E,11Z,14Z)-icosatrienoyl-CoA + H2O 4.2.1.134 very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase

[glycerolipid]-(11Z,14Z)-icosadienoate + O2 + ferricytochrome_b5 + H+ <=> [glycerolipid]-di-homo-gamma-linolenate + H2O + ferricytochrome_b5 1.14.19.4 acyl-lipid (11-3)-desaturase

(3R,11Z,14Z)-3-hydroxyicosadienoyl-CoA + NADP+ <=> (11Z,14Z)-3-oxoicosadienoyl-CoA + NADPH + H+ 1.1.1.330 very-long-chain 3-oxoacyl-CoA reductase

malonyl-CoA + linoleoyl-CoA + H+ <=> (11Z,14Z)-3-oxoicosadienoyl-CoA + CO2 + CoA 2.3.1.199 very-long-chain 3-oxoacyl-CoA synthase

(11Z,14Z)-icosa-11,14-dienoyl-CoA + glycerolipid <=> [glycerolipid]-(11Z,14Z)-icosadienoate + CoA 2.3.1

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